Publications | Pattbiraman Lab 1

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PATTABIRAMAN
NEURODEVELOPMENTAL
LABORATORY

PUBLICATIONS

"In this review, we describe recent advances in characterizing human and primate genetic and cellular innovations"

01

Luria, V., Ma, S., Shibata, M., Pattabiraman, K*., Sestan, N.* (2023) Molecular and cellular mechanisms of human cortical connectivity. Current Opinion in Neurobiology, Volume 80 (102699) (*Shared Corresponding Authors)

02

"This integrated approach has laid the foundations to identify a TF network and cortical VZ REs involved in cortical regional patterning"

Ypslanti AR, Pattabiraman K, Catto-Pretta R, Golonzhka O, Lindtner S, Tang K, Jones I, Shen Y, Abnousi A, Juric I, Hu M, Dickel DE, Visel A, Pennachio LA, Hawrylycz M, Thompson L, Zeng H, Barozzi I, Nord A, Rubenstein JLR. (2021) Transcriptional Network Orchestrating Regional Patterning of Cortical Progenitors. PNAS. 118(51)

03

"These findings suggest a genetic and molecular basis for the anterior-posterior cortical gradient and disproportionate increase in the Hominini PFC of dendritic spines"

Shibata, M., Pattabiraman, K., Muchnik, S.K., Kaur, N., Morozov, Y.M., Cheng, X., Waxman, S.G., Sestan, N. (2021) Hominini-Specific Regulation of CBLN2 Increases Prefrontal Synaptogenesis. Nature. 598, 489–494.

"these findings show that retinoic acid signalling has a critical role in the development of the PFC and, potentially, in its evolutionary expansion."

04

*Shibata, M*., Pattabiraman, K*., Lorente-Galdos, B, Andrijevic, D., Kim, SK., Kaur, N., Muchnik, S.K, Xing, X., Santpere, G., Sousa A.M.M, Sestan, N., (2021) Regulation of Prefrontal Patterning, Connectivity, and Synaptogenesis by Retinoic acid. Nature. 598, 483-488 (*Shared First Authors)

05

"the same evolutionary changes that allowed us to develop these valuable skills made humans susceptible to neurodevelopmental and neurodegenerative disease."

Pattabiraman, K., Muchnik, SM., Sestan, NS., The Evolution of the Human Brain and Disease Suspectibility. (2020) Curr. Opin. in Genetics and Development. 65: 91-97.

06

"These findings suggest a genetic and molecular basis for the anterior-posterior cortical gradient and disproportionate increase in the Hominini PFC of dendritic spines"

Nord, A.S., Pattabiraman, K., Visel, A., Rubenstein, J.L.R. (2014) Genomic Perspectives of Transcriptional Regulation in Forebrain Development. Neuron. 85(1):27-47

07

"We provide evidence that small enhancer elements active in protodomains integrate broad transcriptional information."

Pattabiraman, K., Golonzhka, O., Lindtner, S., Nord, A.S., Taher, L., Hoch, R., Silberberg, S.N., Zhang, D., Chen, B., Zeng, H.K., Pennacchio, L.A., Puelles, L., Visel, A., Rubenstein, J.L.R. (2014) Transcriptional Regulation of Enhancers Active in Protodomains of the Developing Cerebral Cortex. Neuron. 82(5):989-1003.

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